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在针对性药物问世前，治疗手段十分有限且充满挑战。外科肢体延长术创伤性强、风险高，且行业内尚未形成统一诊疗共识；重组人生长激素（rhGH）虽能在一定程度上改善生长状况，但疗效有限，治疗2年后骨骼生长的有益作用便会减弱，还存在显著的长期副作用。
Just over five years ago, Dr. Becky Kennedy did not have an Instagram account. The married mother of three was a practicing psychologist in Manhattan who counseled families in person. But as the COVID pandemic trapped parents at home with restless kids, she launched herself on Instagram, taking to the masses what would become her signature parenting concepts: modeling emotional regulation, setting boundaries, and recognizing so-called “deeply feeling” kids who are, in her words, “more porous to the world.” A few months later, she started a company, Good Inside—a nod to her belief that all children are good inside.